Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Morphoceuticals

Biotech

Morphoceuticals

Morphoceuticals targets native bioelectrical and biochemical pathways to develop novel therapies that access core aspects of our biological operating system. Building on our success regenerating functioning limbs using topical administration of ion channel modulators, we aim to achieve transformative therapeutic outcomes by leveraging computational control of our bioelectric programming, and triggering developmental pathways too complex to micromanage.

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Flipside Crypto

FinTech

Flipside Crypto

Flipside enables blockchains to live up to their full potential, by decoding and explaining blockchain behaviors. Our proprietary process extracts all of the data from blockchains and applies labels to transactions in order to identify and understand on-chain behaviors. The data is then streamed into our Business Intelligence Dashboards, to provide a clear view of real-time stakeholder behaviors and all asset flows. Flipside provides analytics to more than 80 cryptocurrency organizations and distributes ratings products via partners such as CoinMarketCap, Messari, MarketWatch and TheStreet. Flipside Crypto is backed by True Ventures, Founder Collective, CoinBase Ventures, Digital Currency Group, Galaxy Digital, and other investors.

Cellino

Biotech

Cellino

Cellino is building a scalable, automated biomanufacturing system for potentially curative personalized cell therapies. Cellino’s vision is to enable healthier lives worldwide with personalized treatments derived from induced pluripotent stem cells (iPSCs), which can serve as the basis for therapies for a host of chronic degenerative diseases, including vision loss and Parkinson's disease.

HqO

Real Estate

HqO

HqO is transforming how people connect with each other and the places they work. The HqO Workplace Experience Platform makes it easy for companies and commercial property teams to create modern workplaces through world-class amenities and services that allow people to thrive and do their best work. Active in over 200 million square feet in 25 countries, 57% of the Fortune 100 rely on HqO to enhance their workplace experiences, improve employee satisfaction, and drive operational excellence.

Iterative Health

Healthcare

Iterative Health

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

Spoiler Alert

Software

Spoiler Alert

Transforming excess inventory from a problem into a profit. Spoiler Alert is a B2B sales software company helping CPG manufacturers and distributors to manage excess and slow-moving inventory by digitizing the liquidation process. Our goal is to help our customers recover value for products that otherwise would be wasted, allowing them to increase profits, strengthen customer relationships, increase the effectiveness of supply chain managers, and allow for more accurate demand planning. Founded by alumni of MIT, Spoiler Alert works with some of the world's largest companies, including Campbell Soup Company, Danone North America, HelloFresh, KeHE Distributors, Kraft Heinz, Mondelēz, Johnsonville, and Nestlé, along with a growing network of discount channels committed to increasing affordable food access.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.