Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Dispense

eCommerce

Dispense

Dispensaries know their customers better than anyone. Dispensary software should give them the flexibility and control needed to make the right decisions and offer exceptional service. Dispense provides cannabis businesses with simple-to-use tools to boost sales and manage operations - on your own terms. The eCommerce software empowers dispensaries to sell online, increase traffic, build customer relationships, and scale businesses. And with our customizable dispensary management functionality, everything integrates easily into your specific operation. Dispense is not a marketplace; you always own your data, so your efforts never benefit your competitors. That means better customer relationships and more online visibility.

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Scipher Medicine

Healthcare

Scipher Medicine

Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don’t respond to the treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology and not based on symptoms, disease classification, or medical bias. A simple test predicts which drug he/she will respond to, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.

Provengo

SaaS

Software Development

Provengo

We develop tools for system specification, validation, and correct-by-construction workflow automation, based on groundbreaking - yet friendly - formal methods.

Iterative Health

Healthcare

Iterative Health

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

Sense Energy

Electronics

Sense Energy

Sense's mission is to make all homes intelligent by keeping people informed about what's happening in their homes and helping to make them safer, more efficient, and more reliable. Sense was born from the simple idea that people should know what's happening in their homes. We track calories, footsteps, mpg's yet we know so little about the place where we spend so much time. Energy efficiency and home automation begin with information. We built the Sense home energy monitor to provide people with information about their homes in the simplest, most helpful way possible.

Codametrix

Software

Healthcare

Codametrix

CodaMetrix is at the forefront of revolutionizing the medical coding industry through its AI-driven solutions. As a recognized leader, we proudly hold the No. 1 position in the “Reduce Cost of Care” category in the 2023 KLAS Emerging Solutions Report. Our flagship platform, CMX, is a multi-specialty coding AI-platform designed to seamlessly translate clinical information into precise medical codes, catering to both fee-for-service and value-based care models.

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.