Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Hourwork

HR Tech

Hourwork

HourWork offers a new, better way to hire and retain hourly workers in today’s understaffed world. Our best-in-class recruitment and retention solutions help match employers with top hourly talent, uncover what matters most to employees, and automatically check in at key milestones to prevent early attrition. Our name is rooted in our commitment to celebrate and build the interdependent relationship between employers and employees. We partner with clients who see themselves as skill providers and who have a deep belief that their business is most successful when their employees feel successful, too. This understanding – coupled with our advanced HourWork technology – differentiates our customers from the abundance of employers ready to hire today as an employer of choice.

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Mainstay

At Mainstay, we believe one conversation can spark a brighter future. Our Engagement Platform makes it easy for colleges and businesses to start and measure conversations that drive action at scale. From our rigorous research methods to our Behavioral Intelligence framework — everything we do is designed to help people take the next step toward achieving their goals.

Spoiler Alert

Software

Spoiler Alert

Transforming excess inventory from a problem into a profit. Spoiler Alert is a B2B sales software company helping CPG manufacturers and distributors to manage excess and slow-moving inventory by digitizing the liquidation process. Our goal is to help our customers recover value for products that otherwise would be wasted, allowing them to increase profits, strengthen customer relationships, increase the effectiveness of supply chain managers, and allow for more accurate demand planning. Founded by alumni of MIT, Spoiler Alert works with some of the world's largest companies, including Campbell Soup Company, Danone North America, HelloFresh, KeHE Distributors, Kraft Heinz, Mondelēz, Johnsonville, and Nestlé, along with a growing network of discount channels committed to increasing affordable food access.

Asimov

Biotech

Asimov

Headquartered in Boston, Asimov's mission is to advance humanity's ability to design living systems, enabling biotechnologies with outsized societal benefit. The company is developing a synthetic biology platform – from cells to software – to design and manufacture next-generation therapeutics, including biologics, cell/gene therapies, and RNA. Founded by bioengineers from MIT and Boston University, the company has raised over $200 million from top institutional investors including Andreessen Horowitz, CPP Investments, Horizons Ventures, and Fidelity Management & Research Company. Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.

Blues Wireless

IoT

Blues Wireless

Blues.io stands at the pinnacle of IoT wireless communication, ardently dedicated to transforming physical entities into data-rich, intelligent services. Their diverse product suite, encompassing the versatile Notecards, Notecarriers, and the secure Notehub platform, seamlessly integrates with multiple sectors, from healthcare and energy management to electric vehicle infrastructure. Emphasizing swift deployment, robust security, and effortless scalability, Blues.io ensures businesses can seamlessly initiate and expand their IoT ventures. Navigating the intricate realm of IoT, their solutions have earned the trust of over 900 global enterprises, attesting to their unwavering commitment to innovation and excellence. With Blues.io as an ally, companies are not merely adopting state-of-the-art technology; they are becoming part of a movement that envisions a smarter, interconnected world, where efficiency and innovation converge to set new benchmarks.

Overjet

Overjet is pioneering the next era of dentistry. Modern DSOs and insurance companies are realizing the clinical and operational value of innovative technologies and moving towards smart operations that leverage artificial intelligence. Guided by a patient-centric AI, Overjet’s FDA-cleared platform offers more data points in x-rays than previously possible. It integrates with major practice management and imaging systems to guide clinicians to arrive at precise & accurate diagnostic decisions, better care and patient outcomes that drive dentistry forward. With data-driven diagnoses being the key to success, Overjet enables clinicians to achieve higher clinical accuracy, precision, and consistency. When dentists see objective confirmation of a diagnosis they made, they feel more confident, and patients know they can trust their doctors. Building on formative experiences with MIT and Harvard School of Dental Medicine, Overjet was founded on the vision to enhance clinical decision-making to improve oral health. Every day, some of the largest DSOs, dental groups, and insurance companies rely on accurate information provided by Overjet to deliver care and services.

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Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.