Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

Join Discover

Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Scipher Medicine

Healthcare

Scipher Medicine

Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don’t respond to the treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology and not based on symptoms, disease classification, or medical bias. A simple test predicts which drug he/she will respond to, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.

Details

BlockJoy

Blockchain

BlockJoy

BlockJoy allows you to deploy and run your own blockchain nodes on any infrastructure you choose. It started as a project to manager staking with friends and family. We built advanced tooling to optimize validator management for teams of two. But, due to the sheer difficulty of installing and running nodes, our little VaaS company grew crazy fast. We quickly realized that VaaS can’t work for a network because it centralizes control. We turned our platform into a SaaS tool so that anyone could launch and run their own node with full control over where and on what infrastructure it runs. Now, network operators can run their own nodes; BlockJoy just takes the headaches away.

Tomorrow.io

Software

Climate Tech

Tomorrow.io

Tomorrow.io is the world’s leading Weather and Climate Security Platform, equipping humanity with the weather intelligence needed to thrive and adapt in an era of climate crisis. Through predictive and actionable insights, teams adapt to any weather-related challenge at scale, both in real-time and in advance of business impact. Customers, including Uber, Delta, National Grid, and more, use Tomorrow.io to significantly improve operational efficiency, automate risk management, and customize resiliency plans to meet sustainability goals.

Paperless Parts Inc

Manufacturing

Paperless Parts Inc

Paperless Parts is a Boston-based Series B SaaS company backed by OpenView leading the digital transformation for custom part manufacturers. Our cloud-based software helps manufacturers increase revenue and win more business. Paperless Parts' patented technology and proprietary geometry engine unlock hidden insights that enable job shop manufacturers to modernize and grow their businesses. Paperless Parts integrates with your ERP system to level up how you quote and communicate with customers by rapidly pinpointing manufacturability issues, creating quotes, and processing orders for additive manufacturing, sheet metal fabrication, and CNC machining production processes.

JellyFish

Software

JellyFish

Jellyfish is the pioneer Engineering Management Platform that enables engineering leaders to align engineering work with strategic business objectives. By analyzing engineering signals and contextual business data, Jellyfish provides complete visibility into engineering organizations, the work they do, and how they operate. Companies like SessionM (A Mastercard Company) and Toast use Jellyfish to optimize the allocation of engineering resources to focus their teams on what matters most to the business.

HqO

Real Estate

HqO

HqO is transforming how people connect with each other and the places they work. The HqO Workplace Experience Platform makes it easy for companies and commercial property teams to create modern workplaces through world-class amenities and services that allow people to thrive and do their best work. Active in over 200 million square feet in 25 countries, 57% of the Fortune 100 rely on HqO to enhance their workplace experiences, improve employee satisfaction, and drive operational excellence.

Details

Go to Directory

Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.