Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Asimov

Biotech

Asimov

Headquartered in Boston, Asimov's mission is to advance humanity's ability to design living systems, enabling biotechnologies with outsized societal benefit. The company is developing a synthetic biology platform – from cells to software – to design and manufacture next-generation therapeutics, including biologics, cell/gene therapies, and RNA. Founded by bioengineers from MIT and Boston University, the company has raised over $200 million from top institutional investors including Andreessen Horowitz, CPP Investments, Horizons Ventures, and Fidelity Management & Research Company. Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.

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Fertu

Software

Healthcare

Fertu

Fertu is transforming user and patient outreach for digital health companies, health plans and employers with a marketing automation platform that increases enrollment and access to care while lowering cost and effort. Built by healthcare marketers, for healthcare marketers, Fertu solves the toughest challenges of multi-channel touches across the campaign lifecycle to increase user acquisition and enrollment. And Fertu helps benefits administrators to centralize and simplify the management of their various digital health providers.

FireCompass

Software

FireCompass

FireCompass is a SaaS platform for Continuous Automated Red Teaming (CART) & Attack Surface Management (ASM). It continuously indexes and monitors the deep, dark & surface web to map out an organization's digital attack surface including Shadow IT blind spots. The platform then automatically launches safe multi-stage attacks, mimicking a real attacker, to help identify attack paths before hackers do. The platform eliminates the need for multiple tools and significant manual effort while providing continuous and proactive security. FireCompass is a cutting-edge cybersecurity platform that focuses on continuous pen testing and red teaming. Their services ensure that businesses take a proactive approach towards their security, testing not just a fraction but the entirety of their external attack surfaces. This comprehensive approach ensures that peripheral assets, which might typically remain untested for extended periods, are continuously monitored. FireCompass is trusted by Fortune 500 companies, including top telecom companies in the USA, leading banks, financial services, insurance providers, IT/ITES companies, and major players in manufacturing and e-commerce.

Activ Surgical

Healthcare

Activ Surgical

Activ Surgical is a digital surgery pioneer, envisioning a future of collaborative surgery, with surgical intelligence empowering scopes and robots to see what humans cannot see. The top surgeons in the world cannot be everywhere, but with Activ Surgical, their data and insights can be. Founded in 2017, Activ Surgical completed the world ￃﾢ￢ﾂﾬ￢ﾄﾢs first autonomous robotic surgery of soft tissue and is building hardware-agnostic surgical software that allows surgical systems to collaborate with surgeons.

Hourwork

HR Tech

Hourwork

HourWork offers a new, better way to hire and retain hourly workers in today’s understaffed world. Our best-in-class recruitment and retention solutions help match employers with top hourly talent, uncover what matters most to employees, and automatically check in at key milestones to prevent early attrition. Our name is rooted in our commitment to celebrate and build the interdependent relationship between employers and employees. We partner with clients who see themselves as skill providers and who have a deep belief that their business is most successful when their employees feel successful, too. This understanding – coupled with our advanced HourWork technology – differentiates our customers from the abundance of employers ready to hire today as an employer of choice.

1upHealth

Healthcare

1upHealth

1upHealth provides the healthcare industry’s most sophisticated FHIR-enabled health data platform for claims and clinical data acquisition, exchange, and compute. From leading health plans and state Medicaid agencies to innovative digital health organizations and top performing ACOs, over 75 health organizations rely on 1upHealth to meet evolving regulatory requirements and optimize claims and clinical data-driven initiatives. With the push towards digital quality measures, population health analytics, value-based contracts, and better healthcare experiences, the 1up managed platform helps our customers to meet the growing demands for data access and connectivity.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.