Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

BlockJoy

Blockchain

BlockJoy

BlockJoy allows you to deploy and run your own blockchain nodes on any infrastructure you choose. It started as a project to manager staking with friends and family. We built advanced tooling to optimize validator management for teams of two. But, due to the sheer difficulty of installing and running nodes, our little VaaS company grew crazy fast. We quickly realized that VaaS can’t work for a network because it centralizes control. We turned our platform into a SaaS tool so that anyone could launch and run their own node with full control over where and on what infrastructure it runs. Now, network operators can run their own nodes; BlockJoy just takes the headaches away.

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Morphoceuticals

Biotech

Morphoceuticals

Morphoceuticals targets native bioelectrical and biochemical pathways to develop novel therapies that access core aspects of our biological operating system. Building on our success regenerating functioning limbs using topical administration of ion channel modulators, we aim to achieve transformative therapeutic outcomes by leveraging computational control of our bioelectric programming, and triggering developmental pathways too complex to micromanage.

Overjet

Overjet is pioneering the next era of dentistry. Modern DSOs and insurance companies are realizing the clinical and operational value of innovative technologies and moving towards smart operations that leverage artificial intelligence. Guided by a patient-centric AI, Overjet’s FDA-cleared platform offers more data points in x-rays than previously possible. It integrates with major practice management and imaging systems to guide clinicians to arrive at precise & accurate diagnostic decisions, better care and patient outcomes that drive dentistry forward. With data-driven diagnoses being the key to success, Overjet enables clinicians to achieve higher clinical accuracy, precision, and consistency. When dentists see objective confirmation of a diagnosis they made, they feel more confident, and patients know they can trust their doctors. Building on formative experiences with MIT and Harvard School of Dental Medicine, Overjet was founded on the vision to enhance clinical decision-making to improve oral health. Every day, some of the largest DSOs, dental groups, and insurance companies rely on accurate information provided by Overjet to deliver care and services.

Activ Surgical

Healthcare

Activ Surgical

Activ Surgical is a digital surgery pioneer, envisioning a future of collaborative surgery, with surgical intelligence empowering scopes and robots to see what humans cannot see. The top surgeons in the world cannot be everywhere, but with Activ Surgical, their data and insights can be. Founded in 2017, Activ Surgical completed the world ￃﾢ￢ﾂﾬ￢ﾄﾢs first autonomous robotic surgery of soft tissue and is building hardware-agnostic surgical software that allows surgical systems to collaborate with surgeons.

Stavvy

Software

Stavvy

Stavvy helps real estate professionals grow their business and ditch the paper process. The Stavvy platform makes it easy for you to work and collaborate with lending, title/settlement, notarial, and loan servicing partners. Together in one secure platform, you’ll have the tools to boost productivity and dismantle communication silos. Our feature line includes must-have tools like eSign, RON, eRecording, digital audit trail, and a proprietary Eligibility Engine. Recognized for its innovation, Stavvy has played a pivotal role in digital real estate closings, making processes more cost-effective and efficient for all stakeholders involved. As the real estate industry continues to evolve, Stavvy stands as a beacon of digital transformation, ensuring seamless transactions and heightened customer satisfaction.

Flipside Crypto

FinTech

Flipside Crypto

Flipside enables blockchains to live up to their full potential, by decoding and explaining blockchain behaviors. Our proprietary process extracts all of the data from blockchains and applies labels to transactions in order to identify and understand on-chain behaviors. The data is then streamed into our Business Intelligence Dashboards, to provide a clear view of real-time stakeholder behaviors and all asset flows. Flipside provides analytics to more than 80 cryptocurrency organizations and distributes ratings products via partners such as CoinMarketCap, Messari, MarketWatch and TheStreet. Flipside Crypto is backed by True Ventures, Founder Collective, CoinBase Ventures, Digital Currency Group, Galaxy Digital, and other investors.

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.