Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

Join Discover

Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Overjet

Overjet is pioneering the next era of dentistry. Modern DSOs and insurance companies are realizing the clinical and operational value of innovative technologies and moving towards smart operations that leverage artificial intelligence. Guided by a patient-centric AI, Overjet’s FDA-cleared platform offers more data points in x-rays than previously possible. It integrates with major practice management and imaging systems to guide clinicians to arrive at precise & accurate diagnostic decisions, better care and patient outcomes that drive dentistry forward. With data-driven diagnoses being the key to success, Overjet enables clinicians to achieve higher clinical accuracy, precision, and consistency. When dentists see objective confirmation of a diagnosis they made, they feel more confident, and patients know they can trust their doctors. Building on formative experiences with MIT and Harvard School of Dental Medicine, Overjet was founded on the vision to enhance clinical decision-making to improve oral health. Every day, some of the largest DSOs, dental groups, and insurance companies rely on accurate information provided by Overjet to deliver care and services.

Details

1upHealth

Healthcare

1upHealth

1upHealth provides the healthcare industry’s most sophisticated FHIR-enabled health data platform for claims and clinical data acquisition, exchange, and compute. From leading health plans and state Medicaid agencies to innovative digital health organizations and top performing ACOs, over 75 health organizations rely on 1upHealth to meet evolving regulatory requirements and optimize claims and clinical data-driven initiatives. With the push towards digital quality measures, population health analytics, value-based contracts, and better healthcare experiences, the 1up managed platform helps our customers to meet the growing demands for data access and connectivity.

UBERDOC

Healthcare

UBERDOC

"Patient choice is the cornerstone of our mission because it strengthens the doctor-patient relationship. When patients are free to choose their doctor, it puts the control back where it belongs, and no patient should ever have to be denied access to the care they need because of insurance restrictions or cost. UBERDOC is built by those on the front lines of medicine to give patients a simpler solution."

Guidesly

Consumer

Guidesly

Experience the great outdoors with Guidesly - the next-generation marketplace that connects you with expert guides for a variety of outdoor activities, from fishing and hunting to ATV/UTV and more. Our website and app (Guidesly Trips) make it easy for you to compare and book trusted guides and discover the perfect adventure tailored to your interests and skill level. Leave the planning to us and trust our experienced guides to lead the way. Guidesly also supports guides by providing innovative solutions to common challenges faced in the outdoor guiding business. Our platform offers powerful tools for guides to manage their businesses more efficiently and effectively so they can focus on what matters most - delivering unforgettable experiences to their guests. Join our community of passionate outdoor enthusiasts and start your next adventure with Guidesly.

Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

Kintent (TrustCloud)

Compliance in business infiltrates every department and every process. Kintent helps automate compliance so that businesses can focus on what they do best. The software offers a risk-based assessment of company data to help identify potential areas of non-compliance. Various workflows and templates are available for different types of compliance needs.

Details

Go to Directory

Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.