Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Iterative Health

Healthcare

Iterative Health

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

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Silvertree

Consumer

Silvertree

Silvertree is on a mission to inspire the world’s aging population. We are developing a wellness wearable platform that provides the right balance of safety, connection, and style for active older adults. Aging is a personal experience, yet aging with dignity and independence so often includes the caring involvement of family and loved ones. That is why we are designing a stylish, wrist-worn wearable that is built for safety and deeply rooted in human connection, across generations. We aim to be the consumer brand associated with vitality, style, and independence for the growing population of fifty-five million Americans ages sixty-five and beyond.

Provengo

SaaS

Software Development

Provengo

We develop tools for system specification, validation, and correct-by-construction workflow automation, based on groundbreaking - yet friendly - formal methods.

Entrada Therapeutics

Biotech

Entrada Therapeutics

Headquartered in Boston’s Seaport community, Entrada Therapeutics is a growing biopharmaceutical company innovating to transform the treatment of devastating diseases through intracellular therapeutics. We’re establishing a new class of medicines, Endosomal Escape Vehicles (EEV™), with the potential to engage intracellular targets that have long been considered inaccessible and undruggable. Our EEV™ therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index.

Zenyai

Software

SaaS

Digital Health

Zenyai

We turn emotions into sounds to help non-verbal and autistic children find their voice and express themselves.

BIY China

Software

Education

BIY China

Build-It-Yourself offers an art and engineering program driven by technology-in-education research at MIT. Our mission is to inspire and guide the next generation of builders to use technology creatively in a unique global laboratory.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.